immunoBON® – Kuhstallpille®
Cattle farms protect against allergies, asthma and atopic eczema by two factors: inhalation of aerosols and drinking unprocessed milk. immunoBON® mimics the positive nutritional effects of raw milk from dairy farms, while excluding the potential harmful effects of unpasteurized milk.
In the lozenge immunoBON® beta-Lactoglobulin is provided in a combination with micronutrients. It is then also called “holoBLG”. The principle of targeted micronutrition allows dietary management of allergies in a completely allergen non-specific manner.
In a double blind placebo-controlled study Dr. Roth-Walter and team could demonstrate that twice daily intake of the immunoBON® lozenge indeed fueled immune cells of pollen allergics and compensated for micronutrient deficiencies in these patients.
As immunoBON® compensated micronutritional deficiencies exactly in allergic immune cells , their function was normalized. Patients therefore also benefited in an allergen-independent way: the intake was associated with improvement of symptoms elicited by pollen, house dust mite and cat allergens.
Model by Prof. L.F. Pacios, Madrid.
EP20140150965, 2014-01-13; US201615111162, 2016-07-12; Method and means for diagnosing and treating allergy. Inventors: Franziska Roth-Walter, Erika Jensen-Jarolim. Cristina Gomez-Casado, Araceli Diaz Perales, Luis Fernandez Pacios, Josef Singer.
Ameliorating Atopy by Compensating Micronutritional Deficiencies in Immune cells: a double-blind placebo-controlled study. Bartosik T, Jensen SA, Afify SM, Bianchini R, Hufnagl K, Hofstetter G, Berger M, Bastl M, Berger U, Rivelles E, Schmetterer K, Eckl-Dorna J, Brkic FF, Vyskocil E, Kramer MF, Guethoff S, Jensen-Jarolim E, Roth-Walter F. JACI in Practice Jul;10(7):1889-1902.e9. 2022 Mar 6:S2213-2198(22)00229-X. doi: 10.1016/j.jaip.2022.02.028.
Targeted micronutrition via holo-BLG based on the farm effect in house dust mite allergic rhinoconjunctivitis patients – first evaluation in a standardized allergen exposure chamber. Bergmann KC, A. Graessel A, Raab J, Banghard W, Krause L, Sylvia Becker S, Sebastian Kugler S, Zuberbier T, Ott VB, Kramer MF, Roth-Walter F, Jensen-Jarolim E, Guethoff S. Allergo Journal International. Published 22 February 2021 DOI:10.1007/s40629-021-00163-9Corpus ID: 231981905
Long-term benefits of targeted micronutrition with the holoBLG lozenge in house dust mite allergic patients. Bergmann KC, Raab J, Krause L, Becker S, Kugler S, Zuberbier T, Roth-Walter F, Jensen-Jarolim E, Kramer MF, Graessel A. AllergoJournal, 2022, https://doi.org/10.1007/s40629-021-00197-z