SMAiCOM® – SMall Animal imaging COMputer – is a laboratory device for completely non-invasive, automated image analysis in small laboratory animal studies. Animal studies are a regulatory requirement in drug development and approval. SMAiCOM® is a patented, automated image analysis technology for the efficient recording of parameters and generation of reports in such studies. It is based on IP from own research and was previously referred to as “Animal imaging Cage”.
Patented technology
Non-invasive monitoring of small lab animals
Automated image analysis
Mandatory in drug development
Made in Austria
Body temperature is an important indicator of local or systemic inflammation, sensed by SMAiCOM® thermo cameras. The thermal images provide data about body temperature, and about 3D activity of the animals, in short- or long-term monitoring. Hence, SMAiCOM® is applicable in pathophysiological, immunological or behavioral studies connected with changes in body temperature and/or physical activity.
Scientific Publications with SMAiCOM® – imaging cage
Retinoic acid-loading of the major birch pollen allergen Bet v 1 may improve specific allergen immunotherapy: In silico, in vitro and in vivo data in BALB/c mice. Hufnagl K, Moussa AS,Wallner M, Hauser M, Wiederstein M, Gadermaier G, Wildner S, Redegeld FA, Hofstetter G, Pali-Schoell I, Roth-Walter F, Pacios LF, Jensen-Jarolim E.
Micronutritional supplementation with a holoBLG-based FSMP (food for special medical purposes)-lozenge alleviates allergic symptoms in BALB/c mice: Imitating the protective farm effect. Moussa AS, Regner A, Pacios LF, Blokhuis BR, Jensen SA, Redegeld FA, Pali-Schoell I, Hufnagl K, Bianchini R, Guethoff S, Kramer MF, Fiocchi A, Dvorak Z, Jensen-Jarolim E and Roth-Walter F. Clin Exp Allergy. 2022;52:426–441.
Bovine Holo-Beta-Lactoglobulin Cross-Protects Against Pollen Allergies in an Innate Manner in BALB/c Mice: Potential Model for the Farm Effect. Sheriene Moussa Afify, Isabella Pali-Schöll, Karin Hufnagl, Gerlinde Hofstetter, Maha Abdel-Rafea El-Bassuoni, Franziska Roth-Walter, Erika Jensen-Jarolim. Frontiers in Immunology 2021, 12: 611474. doi: 10.3389/fimmu.2021.611474.
Anaphylaxis imaging: Non-invasive measurement of temperature and physical activity of small animals. Manzano-Szalai K, Pali-Schöll I, Krishnamurthy D, Flaschberger I, Jensen-Jarolim E. PLoS One 2016 Mar 10;11(3):e0150819. doi: 10.1371/journal.pone.0150819. eCollection 2016.
Adeno-associated virus-like particles as new carriers for B-cell vaccines: testing immunogenicity and safety in BALB/c mice. Manzano-Szalai K, Thell K, Willensdorfer A, Weghofer M, Pfanzagl B, Singer J, Ritter M, Stremnitzer C, Flaschberger I, Michaelis U, Jensen-Jarolim E. Viral Immunology 2014 Nov;27(9):438-48. doi: 10.1089/vim.2014.0059. Epub 2014 Sep 23.
